Control of memory CD4 T cell activation: MHC class II molecules on APCs and CD4 ligation inhibit memory but not naive CD4 T cells.
Memory or antigen-experienced CD4 T cells differ from naive CD4 T cells both phenotypically by cell surface marker expression, and functionally by their dissimilar pattern of cytokine secretion and activation requirements through their T cell receptor (TCR). We show here that activation of memory CD...
Main Authors: | Farber, D, Luqman, M, Acuto, O, Bottomly, K |
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Format: | Journal article |
Language: | English |
Published: |
1995
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