Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues.
Platelet alpha 2-adrenoceptor binding characteristics were investigated in 28 healthy women during the peripartum period. The number of platelet alpha 2-adrenoceptors fell after childbirth, corresponding to a fall in the circulating levels of oestrogen and progesterone. Two-thirds of the women had a...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1983
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| _version_ | 1797069857011793920 |
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| author | Metz, A Stump, K Cowen, P Elliott, J Gelder, MG Grahame-Smith, D |
| author_facet | Metz, A Stump, K Cowen, P Elliott, J Gelder, MG Grahame-Smith, D |
| author_sort | Metz, A |
| collection | OXFORD |
| description | Platelet alpha 2-adrenoceptor binding characteristics were investigated in 28 healthy women during the peripartum period. The number of platelet alpha 2-adrenoceptors fell after childbirth, corresponding to a fall in the circulating levels of oestrogen and progesterone. Two-thirds of the women had an episode of maternity blues. At 7-10 days post partum the platelet alpha 2-adrenoceptor capacity in these subjects was significantly higher than in those women who did not show signs of maternity blues and significantly higher than a control group of normally menstruating women. We conclude that platelet alpha 2-adrenoceptors may be affected by the circulating levels of endogenous oestrogen and progesterone and that a delayed or diminished fall in platelet alpha 2-adrenoceptor capacity after childbirth may be associated with the development of maternity blues. |
| first_indexed | 2024-03-06T22:30:36Z |
| format | Journal article |
| id | oxford-uuid:58247d9b-137a-494c-8cf2-4d7565b2e7cb |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:30:36Z |
| publishDate | 1983 |
| record_format | dspace |
| spelling | oxford-uuid:58247d9b-137a-494c-8cf2-4d7565b2e7cb2022-03-26T17:01:19ZChanges in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:58247d9b-137a-494c-8cf2-4d7565b2e7cbEnglishSymplectic Elements at Oxford1983Metz, AStump, KCowen, PElliott, JGelder, MGGrahame-Smith, DPlatelet alpha 2-adrenoceptor binding characteristics were investigated in 28 healthy women during the peripartum period. The number of platelet alpha 2-adrenoceptors fell after childbirth, corresponding to a fall in the circulating levels of oestrogen and progesterone. Two-thirds of the women had an episode of maternity blues. At 7-10 days post partum the platelet alpha 2-adrenoceptor capacity in these subjects was significantly higher than in those women who did not show signs of maternity blues and significantly higher than a control group of normally menstruating women. We conclude that platelet alpha 2-adrenoceptors may be affected by the circulating levels of endogenous oestrogen and progesterone and that a delayed or diminished fall in platelet alpha 2-adrenoceptor capacity after childbirth may be associated with the development of maternity blues. |
| spellingShingle | Metz, A Stump, K Cowen, P Elliott, J Gelder, MG Grahame-Smith, D Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues. |
| title | Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues. |
| title_full | Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues. |
| title_fullStr | Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues. |
| title_full_unstemmed | Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues. |
| title_short | Changes in platelet alpha 2-adrenoceptor binding post partum: possible relation to maternity blues. |
| title_sort | changes in platelet alpha 2 adrenoceptor binding post partum possible relation to maternity blues |
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