Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.

Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.

11Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1) converts inactive corticosteroids into biologically active corticosteroids, thereby regulating the local concentration of active glucocorticoids, such as cortisol. 11beta-HSD-1 is particularly expressed in adipocytes and liver and appears to...

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Detalles Bibliográficos
Main Authors:	Stulnig, T, Oppermann, U, Steffensen, K, Schuster, G, Gustafsson, J
Formato:	Journal article
Idioma:	English
Publicado:	2002

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