Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.

11Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1) converts inactive corticosteroids into biologically active corticosteroids, thereby regulating the local concentration of active glucocorticoids, such as cortisol. 11beta-HSD-1 is particularly expressed in adipocytes and liver and appears to...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Stulnig, T, Oppermann, U, Steffensen, K, Schuster, G, Gustafsson, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2002