Pathway utilization in response to a site-specific DNA double-strand break in fission yeast.

We have examined the genetic requirements for efficient repair of a site-specific DNA double-strand break (DSB) in Schizosaccharomyces pombe. Tech nology was developed in which a unique DSB could be generated in a non-essential minichromosome, Ch(16), using the Saccharomyces cerevisiae HO-endonuclea...

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Bibliographic Details
Main Authors: Prudden, J, Evans, J, Hussey, S, Deans, B, O'Neill, P, Thacker, J, Humphrey, T
Format: Journal article
Language:English
Published: 2003

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