Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

Systematic epistasis analyses in multifactorial disorders are an important step to better characterize complex genetic risk structures. We conducted a hypothesis-free sex-stratified genome-wide screening for epistasis contributing to Alzheimer's disease (AD) susceptibility. We identified a stat...

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Bibliografski detalji
Glavni autori: Gusareva, E, Twizere, J, Sleegers, K, Dourlen, P, Abisambra, J, Meier, S, Cloyd, R, Weiss, B, Dermaut, B, Bessonov, K, Van Der Lee, S, Carrasquillo, M, Katsumata, Y, Cherkaoui, M, Asselbergh, B, Ikram, M, Mayeux, R, Farrer, L, Haines, J, Pericak-Vance, M, Schellenberg, G, Genetic And Environmental Risk In Alzheimer'S Disease 1 Consortium (GERAD1), Alzheimer'S Disease Genetics Consortium (ADGC), European Alzheimer Disease Initiative Investigators (EADI1 Consortium), Sims, R, Williams, J, Amouyel, P, Van Duijn, C, Ertekin-Taner, N, Van Broeckhoven, C, Dequiedt, F, Fardo, D, Lambert, J, Van Steen, K
Format: Journal article
Jezik:English
Izdano: Elsevier 2018

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