Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study.
OBJECTIVE: Several lines of evidence suggest that estrogens influence the development of osteoarthritis (OA). The aim of this study was to explore the association of two common polymorphisms within the aromatase (CYP19A1) and estrogen receptor (ER) alpha (ESR1) genes with severe OA of the lower lim...
Main Authors: | Riancho, J, García-Ibarbia, C, Gravani, A, Raine, E, Rodríguez-Fontenla, C, Soto-Hermida, A, Rego-Perez, I, Dodd, A, Gómez-Reino, J, Zarrabeitia, M, Garcés, C, Carr, A, Blanco, F, González, A, Loughlin, J |
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Format: | Journal article |
Language: | English |
Published: |
2010
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