Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding

Human prolyl hydroxylases are involved in the modification of transcription factors, procollagen, and ribosomal proteins, and are current medicinal chemistry targets. To date, there are few reports on inhibitors selective for the different types of prolyl hydroxylases. Here we report a structurally...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Thinnes, C, Lohans, C, Abboud, M, Yeh, T, Tumber, A, Nowak, R, Attwood, M, Cockman, M, Oppermann, U, Loenarz, C, Schofield, C
Aineistotyyppi: Journal article
Julkaistu: Wiley 2018