Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding

Human prolyl hydroxylases are involved in the modification of transcription factors, procollagen, and ribosomal proteins, and are current medicinal chemistry targets. To date, there are few reports on inhibitors selective for the different types of prolyl hydroxylases. Here we report a structurally...

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書目詳細資料
Main Authors: Thinnes, C, Lohans, C, Abboud, M, Yeh, T, Tumber, A, Nowak, R, Attwood, M, Cockman, M, Oppermann, U, Loenarz, C, Schofield, C
格式: Journal article
出版: Wiley 2018

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