Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Manylion Llyfryddiaeth
Prif Awduron:	Locklin, R, Russell, R, Croucher, P, Edwards, C
Fformat:	Conference item
Cyhoeddwyd:	2007

Eitemau Tebyg

Cells of the bone marrow microenvironment protect myeloma cells from apoptosis induced by TRAIL but not by agonists of TRAIL death receptors.
gan: Locklin, R, et al.
Cyhoeddwyd: (2005)

Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.
gan: Locklin, R, et al.
Cyhoeddwyd: (2007)

Lactoferrin protects osteoblasts and osteocytes from apoptosis
gan: Locklin, R, et al.
Cyhoeddwyd: (2009)

Differential sensitivity of normal osteoblast-like cells and osteosarcoma cells to TRAIL and an agonist antibody to TRAIL receptor-2
gan: Locklin, R, et al.
Cyhoeddwyd: (2005)

The potent bisphosphonate ibandronate does not induce myeloma cell apoptosis in a murine model of established multiple myeloma.
gan: Shipman, C, et al.
Cyhoeddwyd: (2000)

Myeloma cells isolated from patients with multiple myeloma express osteoprotegerin ligand.
gan: Shipman, C, et al.
Cyhoeddwyd: (2000)

Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity.
gan: Shipman, C, et al.
Cyhoeddwyd: (1997)

Sulforaphane - A new therapy for mutliple myeloma?
gan: Locklin, R, et al.
Cyhoeddwyd: (2008)

The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
gan: Shipman, C, et al.
Cyhoeddwyd: (1998)

Myeloma cells decrease EphB4 expression in osteoblasts; A novel mechanism for regulation of bone formation in multiple myeloma
gan: Bates, A, et al.
Cyhoeddwyd: (2007)

Myeloma cells decrease EphB4 expression in osteoblasts: A novel mechanism for regulation of bone formation in multiple myeloma
gan: Bates, A, et al.
Cyhoeddwyd: (2007)

Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis.
gan: Locklin, R, et al.
Cyhoeddwyd: (2007)

Apomine, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo.
gan: Edwards, C, et al.
Cyhoeddwyd: (2007)

Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
gan: Zhigang Xie, et al.
Cyhoeddwyd: (2011-01-01)

N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation
gan: Richard W.J. Groen, et al.
Cyhoeddwyd: (2011-11-01)

Tumor-host cell interactions in the bone disease of myeloma.
gan: Fowler, J, et al.
Cyhoeddwyd: (2011)

BIM is a novel regulator of glucocorticoid-induced apoptosis in osteoblasts
gan: Espina, B, et al.
Cyhoeddwyd: (2006)

Osteoblast suppression in multiple myeloma bone disease
gan: Juraj Adamik, et al.
Cyhoeddwyd: (2018-11-01)

Metformin and FTY720 Synergistically Induce Apoptosis in Multiple Myeloma Cells
gan: Yi Zhao, et al.
Cyhoeddwyd: (2018-07-01)

Systemic Dysfunction of Osteoblast Differentiation in Adipose-Derived Stem Cells from Patients with Multiple Myeloma
gan: Véronique Béréziat, et al.
Cyhoeddwyd: (2019-05-01)

EphB4 Expression in Osteoblasts is Regulated by Myeloma Cells and the Wnt Signaling Pathway.
gan: Bates, A, et al.
Cyhoeddwyd: (2008)

5T2MM murine myeloma cells and CD138+ve human myeloma cells promote osteoclastic activity rather than osteoclast formation in vitro
gan: Mueller, G, et al.
Cyhoeddwyd: (2004)

Human Myeloma Cell Lines Induce Osteoblast Downregulation of CD99 Which Is Involved in Osteoblast Formation and Activity
gan: Angela Oranger, et al.
Cyhoeddwyd: (2015-01-01)

Myeloma cells can promote osteoclastic activity rather than osteoclast recruitment in vitro; Evidence from the 5T2MM murine model of myeloma
gan: Mueller, G, et al.
Cyhoeddwyd: (2004)

APOMINE (TM), a novel inhibitor of the meyalonate/isoprenoid pathway, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of the myeloma disease in vivo.
gan: Croucher, P, et al.
Cyhoeddwyd: (2002)

Natural killer cells activity against multiple myeloma cells is modulated by osteoblast-induced IL-6 and IL-10 production
gan: Christopher Uhl, et al.
Cyhoeddwyd: (2022-03-01)

Osteoprotegerin (OPG) is a soluble decoy receptor for TRAIL/Apo2L and can inhibit TRAIL/Apo2L-induced apoptosis of human myeloma cells in vitro.
gan: Shipman, C, et al.
Cyhoeddwyd: (2002)

Myeloma cell growth suppression by osteoblast-derived extracellular vesicles: the creation of a non-permissive niche for myeloma cells by bone-forming osteoblasts
gan: SooHa Kim, et al.
Cyhoeddwyd: (2025-01-01)

Anti-tumour activity of bisphosphonates in human myeloma cells.
gan: Shipman, C, et al.
Cyhoeddwyd: (1998)

Bisphosphonates--mechanisms of action in multiple myeloma.
gan: Shipman, C, et al.
Cyhoeddwyd: (2000)

NE10790, a phosphonocarboxylate analogue of risedronate, induces human myeloma cell apoptosis in vitro
gan: Roelofs, A, et al.
Cyhoeddwyd: (2004)

Nitrogen-containing bisphosphonates induce apoptosis in human bone marrow-derived myeloma cells in vitro by inhibiting protein prenylation.
gan: Gordon, S, et al.
Cyhoeddwyd: (1999)

Regulation of bim in glucocorticoid-mediated osteoblast apoptosis.
gan: Espina, B, et al.
Cyhoeddwyd: (2008)

Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
gan: Blomhoff Rune, et al.
Cyhoeddwyd: (2011-07-01)

Tumour cells isolated from patients with multiple myeloma express the critical osteoclastogenic factor, RANKL.
gan: Shipman, C, et al.
Cyhoeddwyd: (2000)

Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells.
gan: Shipman, C, et al.
Cyhoeddwyd: (2003)

Myeloma cells can down-regulate release of osteoprotegerin (OPG) from human bone cells - A contributing factor in myeloma bone loss?
gan: Shipman, C, et al.
Cyhoeddwyd: (2002)

Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche.
gan: Wenting Zhang, et al.
Cyhoeddwyd: (2015-01-01)

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
gan: Nur Mahammad, et al.
Cyhoeddwyd: (2021-12-01)

Targeting proliferating cell nuclear antigen and its protein interactions induces apoptosis in multiple myeloma cells.
gan: Rebekka Müller, et al.
Cyhoeddwyd: (2013-01-01)