Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Bibliografiska uppgifter
Huvudupphovsmän:	Locklin, R, Russell, R, Croucher, P, Edwards, C
Materialtyp:	Conference item
Publicerad:	2007

Liknande verk

Cells of the bone marrow microenvironment protect myeloma cells from apoptosis induced by TRAIL but not by agonists of TRAIL death receptors.
av: Locklin, R, et al.
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Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.
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Lactoferrin protects osteoblasts and osteocytes from apoptosis
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Differential sensitivity of normal osteoblast-like cells and osteosarcoma cells to TRAIL and an agonist antibody to TRAIL receptor-2
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The potent bisphosphonate ibandronate does not induce myeloma cell apoptosis in a murine model of established multiple myeloma.
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Myeloma cells isolated from patients with multiple myeloma express osteoprotegerin ligand.
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Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity.
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The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
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Myeloma cells decrease EphB4 expression in osteoblasts; A novel mechanism for regulation of bone formation in multiple myeloma
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Myeloma cells decrease EphB4 expression in osteoblasts: A novel mechanism for regulation of bone formation in multiple myeloma
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Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis.
av: Locklin, R, et al.
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Apomine, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo.
av: Edwards, C, et al.
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Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.
av: Zhigang Xie, et al.
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N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation
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Tumor-host cell interactions in the bone disease of myeloma.
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BIM is a novel regulator of glucocorticoid-induced apoptosis in osteoblasts
av: Espina, B, et al.
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Osteoblast suppression in multiple myeloma bone disease
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Metformin and FTY720 Synergistically Induce Apoptosis in Multiple Myeloma Cells
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Systemic Dysfunction of Osteoblast Differentiation in Adipose-Derived Stem Cells from Patients with Multiple Myeloma
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EphB4 Expression in Osteoblasts is Regulated by Myeloma Cells and the Wnt Signaling Pathway.
av: Bates, A, et al.
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5T2MM murine myeloma cells and CD138+ve human myeloma cells promote osteoclastic activity rather than osteoclast formation in vitro
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Human Myeloma Cell Lines Induce Osteoblast Downregulation of CD99 Which Is Involved in Osteoblast Formation and Activity
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Myeloma cells can promote osteoclastic activity rather than osteoclast recruitment in vitro; Evidence from the 5T2MM murine model of myeloma
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APOMINE (TM), a novel inhibitor of the meyalonate/isoprenoid pathway, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of the myeloma disease in vivo.
av: Croucher, P, et al.
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Natural killer cells activity against multiple myeloma cells is modulated by osteoblast-induced IL-6 and IL-10 production
av: Christopher Uhl, et al.
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Osteoprotegerin (OPG) is a soluble decoy receptor for TRAIL/Apo2L and can inhibit TRAIL/Apo2L-induced apoptosis of human myeloma cells in vitro.
av: Shipman, C, et al.
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Myeloma cell growth suppression by osteoblast-derived extracellular vesicles: the creation of a non-permissive niche for myeloma cells by bone-forming osteoblasts
av: SooHa Kim, et al.
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Anti-tumour activity of bisphosphonates in human myeloma cells.
av: Shipman, C, et al.
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Bisphosphonates--mechanisms of action in multiple myeloma.
av: Shipman, C, et al.
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NE10790, a phosphonocarboxylate analogue of risedronate, induces human myeloma cell apoptosis in vitro
av: Roelofs, A, et al.
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Nitrogen-containing bisphosphonates induce apoptosis in human bone marrow-derived myeloma cells in vitro by inhibiting protein prenylation.
av: Gordon, S, et al.
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Regulation of bim in glucocorticoid-mediated osteoblast apoptosis.
av: Espina, B, et al.
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Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
av: Blomhoff Rune, et al.
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Tumour cells isolated from patients with multiple myeloma express the critical osteoclastogenic factor, RANKL.
av: Shipman, C, et al.
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Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells.
av: Shipman, C, et al.
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Myeloma cells can down-regulate release of osteoprotegerin (OPG) from human bone cells - A contributing factor in myeloma bone loss?
av: Shipman, C, et al.
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Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche.
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Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
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Targeting proliferating cell nuclear antigen and its protein interactions induces apoptosis in multiple myeloma cells.
av: Rebekka Müller, et al.
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