Osteoblasts protect multiple myeloma cells from T-cell-induced apoptosis

Eitemau Tebyg

• Cells of the bone marrow microenvironment protect myeloma cells from apoptosis induced by TRAIL but not by agonists of TRAIL death receptors.
  gan: Locklin, R, et al.
  Cyhoeddwyd: (2005)
• Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.
  gan: Locklin, R, et al.
  Cyhoeddwyd: (2007)
• Lactoferrin protects osteoblasts and osteocytes from apoptosis
  gan: Locklin, R, et al.
  Cyhoeddwyd: (2009)
• Differential sensitivity of normal osteoblast-like cells and osteosarcoma cells to TRAIL and an agonist antibody to TRAIL receptor-2
  gan: Locklin, R, et al.
  Cyhoeddwyd: (2005)
• The potent bisphosphonate ibandronate does not induce myeloma cell apoptosis in a murine model of established multiple myeloma.
  gan: Shipman, C, et al.
  Cyhoeddwyd: (2000)