Multistep binding of transition metals to the H-N-H endonuclease toxin colicin E9.

Multistep binding of transition metals to the H-N-H endonuclease toxin colicin E9.

We report the first stopped-flow fluorescence analysis of transition metal binding (Co(2+), Ni(2+), Cu(2+), and Zn(2+)) to the H-N-H endonuclease motif within colicin E9 (the E9 DNase). The H-N-H consensus forms the active site core of a number of endonuclease groups but is also structurally homolog...

Detaylı Bibliyografya
Asıl Yazarlar:	Keeble, A, Hemmings, A, James, R, Moore, G, Kleanthous, K
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2002

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