Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism

To explore the functions of RUNX3 single nucleotide polymorphisms (SNPs) associated with ankylosing spondylitis (AS).Individual SNP associations were evaluated in 4230 UK cases. Their effects on transcription factor (TF) binding, transcription regulation, chromatin modifications, gene expression and...

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Hlavní autoři: Vecellio, M, Cortes, A, Roberts, A, Ellis, J, Cohen, C, Knight, J, Brown, M, Bowness, P, Wordsworth, B
Médium: Journal article
Jazyk:English
Vydáno: BMJ Publishing Group 2018