Dominant transplantation tolerance impairs CD8+ T cell function but not expansion.
Alloreactive CD8+ T cells may persist in animals made tolerant of transplanted tissues; their function is controlled through continuous censorship by regulatory CD4+ T cells. We sought to establish the stage at which such censorship operates. We found that monospecific CD8+ T cells introduced into t...
Egile Nagusiak: | Lin, C, Graca, L, Cobbold, S, Waldmann, H |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2002
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Antzeko izenburuak
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Dominant transplantation tolerance. Opinion.
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Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells.
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