Dominant transplantation tolerance impairs CD8+ T cell function but not expansion.

Alloreactive CD8+ T cells may persist in animals made tolerant of transplanted tissues; their function is controlled through continuous censorship by regulatory CD4+ T cells. We sought to establish the stage at which such censorship operates. We found that monospecific CD8+ T cells introduced into t...

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Detalhes bibliográficos
Main Authors: Lin, C, Graca, L, Cobbold, S, Waldmann, H
Formato: Journal article
Idioma:English
Publicado em: 2002

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