Dominant transplantation tolerance impairs CD8+ T cell function but not expansion.
Alloreactive CD8+ T cells may persist in animals made tolerant of transplanted tissues; their function is controlled through continuous censorship by regulatory CD4+ T cells. We sought to establish the stage at which such censorship operates. We found that monospecific CD8+ T cells introduced into t...
Main Authors: | Lin, C, Graca, L, Cobbold, S, Waldmann, H |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2002
|
Registos relacionados
-
Dominant transplantation tolerance. Opinion.
Por: Graca, L, et al.
Publicado em: (2003) -
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance.
Por: Graca, L, et al.
Publicado em: (2002) -
Antibody-induced transplantation tolerance: the role of dominant regulation.
Por: Graca, L, et al.
Publicado em: (2003) -
Approaching tolerance in transplantation
Por: Lin, C, et al.
Publicado em: (2002) -
Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells.
Por: Graca, L, et al.
Publicado em: (2004)