Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line.

Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line.

Show other versions (1)

The neurodegenerative process in Parkinson's disease (PD) is accompanied by the presence of a neuroinflammatory response, which has been suggested as one of the principal components involved in PD progression. In this report we assessed the inflammatory potential of alpha-synuclein, a protein c...

书目详细资料
Main Authors:	Alvarez-Erviti, L, Couch, Y, Richardson, J, Cooper, J, Wood, M
格式:	Journal article
语言:	English
出版:	2011

相似书籍

Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line
由: Alvarez-Erviti, L, et al.
出版: (2011)

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.
由: Alvarez-Erviti, L, et al.
出版: (2011)

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission
由: Alvarez-Erviti, L, et al.
出版: (2011)

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission
由: Alvarez-Erviti, L, et al.
出版: (2011)

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission
由: Lydia Alvarez-Erviti, et al.
出版: (2011-06-01)

The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation.
由: Couch, Y, et al.
出版: (2011)

Modelling of the microglial response to neuronal α-synuclein aggregation
由: Katsikoudi, A
出版: (2022)

The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation
由: Couch Yvonne, et al.
出版: (2011-11-01)

Expression of mutant alpha-synuclein modulates microglial phenotype in vitro
由: Combs Colin K, et al.
出版: (2011-05-01)

Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
由: Pearce Ronald KB, et al.
出版: (2005-06-01)

Correction: Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
由: Pearce Ronald KB, et al.
出版: (2006-04-01)

The Peripheral Inflammatory Response to Alpha-Synuclein and Endotoxin in Parkinson's Disease
由: Alice J. White, et al.
出版: (2018-11-01)

Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures
由: Melanie Barth, et al.
出版: (2021-08-01)

Human induced pluripotent stem cell-derived dopaminergic neurons release alpha-synuclein through neuronal activity
由: Maierdanjiang Nuermaimaiti, et al.
出版: (2025-03-01)

Differential expression of alpha-synuclein in hippocampal neurons.
由: Katsutoshi Taguchi, et al.
出版: (2014-01-01)

Microglial inhibition alleviates alpha-synuclein propagation and neurodegeneration in Parkinson’s disease mouse model
由: Thuy Thi Lai, et al.
出版: (2024-02-01)

Acetylcholine suppresses microglial inflammatory response via $\alpha$7nAChR to protect hippocampal neurons
由: Lin Li, Zhan Liu, Yong-Ying Jiang, Wei-Xing Shen, Yu-Ping Peng, Yi-Hua Qiu
出版: (2019-03-01)

Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies
由: Inês C. Brás, et al.
出版: (2021-02-01)

Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells
由: Chuang Dennis Y, et al.
出版: (2013-01-01)

Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons
由: Heman-Ackah, S, et al.
出版: (2017)

Targeted Extracellular Vesicle Gene Therapy for Modulating Alpha-Synuclein Expression in Gut and Spinal Cord
由: Maria Izco, et al.
出版: (2023-04-01)

Internalization, axonal transport and release of fibrillar forms of alpha-synuclein
由: Gregor Bieri, et al.
出版: (2018-01-01)

Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro
由: Adam J. Bindas, et al.
出版: (2022-12-01)

Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes
由: Paul S. Baxter, et al.
出版: (2021-03-01)

Dynamic transport and localization of alpha-synuclein in primary hippocampal neurons
由: Woods Wendy S, et al.
出版: (2010-02-01)

Linking Alpha-Synuclein to the Actin Cytoskeleton: Consequences to Neuronal Function
由: Marina I. Oliveira da Silva, et al.
出版: (2020-08-01)

Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein
由: Yanina Dening, et al.
出版: (2022-12-01)

Transfer of host-derived alpha synuclein to grafted dopaminergic neurons in rat
由: Jeffrey H. Kordower, et al.
出版: (2011-09-01)

Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.
由: Eric J Benner, et al.
出版: (2008-01-01)

Calcein Release Assay to Measure Membrane Permeabilization by Recombinant Alpha-Synuclein
由: Sayan Dutta, et al.
出版: (2020-07-01)

Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria
由: Ranabir Chakraborty, et al.
出版: (2023-05-01)

Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein.
由: Senior, S, et al.
出版: (2008)

SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine
由: Lin-nan Zhu, et al.
出版: (2018-08-01)

LRRK2 kinase inhibitors reduce alpha-synuclein in human neuronal cell lines with the G2019S mutation
由: Ye Zhao, et al.
出版: (2020-10-01)

Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra.
由: Garcia-Reitboeck, P, et al.
出版: (2013)

The effect of alpha-synuclein knockdown on MPP+ toxicity in models of human neurons.
由: Fountaine, T, et al.
出版: (2008)

Alpha-synuclein expression in oxytocin neurons of young and old bovine brains
由: Yvan Bienvenu NIYONZIMA, et al.
出版: (2024-04-01)

The role of alpha-synuclein in melanin synthesis in melanoma and dopaminergic neuronal cells.
由: Tianhong Pan, et al.
出版: (2012-01-01)

Direct current stimulation enhances neuronal alpha-synuclein degradation in vitro
由: Gessica Sala, et al.
出版: (2021-01-01)

Extracellular alpha-synuclein: Sensors, receptors, and responses
由: Renato Domingues, et al.
出版: (2022-06-01)