Role of cathepsins in Mycobacterium tuberculosis survival in human macrophages

Cathepsins are proteolytic enzymes that function in the endocytic pathway, especially in lysosomes, where they contribute directly to pathogen killing or indirectly, by their involvement in the antigen presentation pathways. Mycobacterium tuberculosis (MTB) is a facultative intracellular pathogen th...

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Podrobná bibliografie
Hlavní autoři: Pires, D, Marques, J, Pombo, J, Carmo, N, Bettencourt, P, Neyrolles, O, Lugo-Villarino, G, Anes, E
Médium: Journal article
Jazyk:English
Vydáno: Nature Publishing Group 2016