Cell-penetrating peptides-based strategies for the delivery of splice redirecting antisense oligonucleotides.
Progress in our understanding of the molecular pathogenesis of human malignancies has provided therapeutic targets amenable to oligonucleotide (ON)-based strategies. Antisense ON-mediated splicing regulation in particular offers promising prospects since the majority of human genes undergo alternati...
Main Authors: | Andaloussi, S, Said Hassane, F, Boisguerin, P, Sillard, R, Langel, U, Lebleu, B |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2011
|
Similar Items
-
Insights into the cellular trafficking of splice redirecting oligonucleotides complexed with chemically modified cell-penetrating peptides.
by: Hassane, F, et al.
Published: (2011) -
Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo
by: Safa Bazaz, et al.
Published: (2021-08-01) -
Perfluoroaryl Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides
by: Wolfe, Justin, et al.
Published: (2020) -
Use of cell-penetrating-peptides in oligonucleotide splice switching therapy.
by: El Andaloussi, SA, et al.
Published: (2012) -
Peptide-mediated cell and in vivo delivery of antisense oligonucleotides and siRNA
by: Järver, P, et al.
Published: (2012)