Characterising the functional role of GATA1short isoform in normal and malignant haematopoiesis
ML-DS and its precursor disease TAM are genetically simple models of acute myeloid leukaemia to study how two or more genetic changes synergize to induce maturation arrest and leukaemic transformation. Both TAM and ML-DS are driven by mutations in the gene encoding the X-linked erythroid-megakaryocy...
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| Format: | Thesis |
| Language: | English |
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2021
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