Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.
The wide spectrum of clinical outcomes following infection with Mycobacterium tuberculosis is largely determined by the host immune response; therefore, we studied several clinically defined groups of individuals (n = 120) that differ in their ability to contain the bacillus. To quantitate M. tuberc...
প্রধান লেখক: | Pathan, A, Wilkinson, K, Klenerman, P, McShane, H, Davidson, R, Pasvol, G, Hill, A, Lalvani, A |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2001
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অনুরূপ উপাদানগুলি
অনুরূপ উপাদানগুলি
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High frequencies of circulating IFN-gamma-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis-infected subjects without disease.
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Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells.
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Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis.
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Ex vivo characterization of early secretory antigenic target 6–specific T cells at sites of active disease in pleural tuberculosis
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