Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.
The wide spectrum of clinical outcomes following infection with Mycobacterium tuberculosis is largely determined by the host immune response; therefore, we studied several clinically defined groups of individuals (n = 120) that differ in their ability to contain the bacillus. To quantitate M. tuberc...
Autors principals: | Pathan, A, Wilkinson, K, Klenerman, P, McShane, H, Davidson, R, Pasvol, G, Hill, A, Lalvani, A |
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Format: | Journal article |
Idioma: | English |
Publicat: |
2001
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