Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.

Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.

The wide spectrum of clinical outcomes following infection with Mycobacterium tuberculosis is largely determined by the host immune response; therefore, we studied several clinically defined groups of individuals (n = 120) that differ in their ability to contain the bacillus. To quantitate M. tuberc...

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Bibliografiske detaljer
Main Authors:	Pathan, A, Wilkinson, K, Klenerman, P, McShane, H, Davidson, R, Pasvol, G, Hill, A, Lalvani, A
Format:	Journal article
Sprog:	English
Udgivet:	2001

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