Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.
The wide spectrum of clinical outcomes following infection with Mycobacterium tuberculosis is largely determined by the host immune response; therefore, we studied several clinically defined groups of individuals (n = 120) that differ in their ability to contain the bacillus. To quantitate M. tuberc...
Những tác giả chính: | Pathan, A, Wilkinson, K, Klenerman, P, McShane, H, Davidson, R, Pasvol, G, Hill, A, Lalvani, A |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2001
|
Những quyển sách tương tự
-
High frequencies of circulating IFN-gamma-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis-infected subjects without disease.
Bằng: Pathan, A, et al.
Được phát hành: (2000) -
Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells.
Bằng: Lalvani, A, et al.
Được phát hành: (2001) -
Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis.
Bằng: Lalvani, A, et al.
Được phát hành: (1998) -
Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load.
Bằng: Millington, K, et al.
Được phát hành: (2007) -
Ex vivo characterization of early secretory antigenic target 6–specific T cells at sites of active disease in pleural tuberculosis
Bằng: Wilkinson, K, et al.
Được phát hành: (2005)