Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells
It has been proposed that endogenous H2S mediates oxygen sensing in chemoreceptors; this study investigates the mechanisms by which H 2S excites carotid body type 1 cells. H2S caused a rapid reversible increase in intracellular calcium with EC50≈6 μM. This [Ca2+]i response was abolished in Ca-free T...
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| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
2012
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