Selective halogenation of pyridines using designed phosphine reagents
Halopyridines are key building blocks for synthesizing pharmaceuticals, agrochemicals, and ligands for metal complexes, but strategies to selectively halogenate pyridine C–H precursors are lacking. We designed a set of heterocyclic phosphines that are installed at the 4-position of pyridines as phos...
Main Authors: | Levy, JN, Alegre-Requena, JV, Liu, R, Paton, RS, McNally, A |
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Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2020
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