Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy.

Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy.

Mouse mutants have a key role in discerning mammalian gene function and modelling human disease; however, at present mutants exist for only 1-2% of all mouse genes. In order to address this phenotype gap, we have embarked on a genome-wide, phenotype-driven, large-scale N-ethyl-N--nitrosourea (ENU) m...

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Autors principals: Isaacs, A, Davies, K, Hunter, A, Nolan, P, Vizor, L, Peters, J, Gale, D, Kelsell, D, Latham, I, Chase, J, Fisher, E, Bouzyk, M, Potter, A, Masih, M, Walsh, F, Sims, M, Doncaster, K, Parsons, C, Martin, J, Brown, S, Rastan, S, Spurr, N, Gray, I
Format: Journal article
Idioma:English
Publicat: 2000

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