A variation in the ghrelin gene increases weight and decreases insulin secretion in tall, obese children.
Ghrelin is a recently recognized gut-brain peptide originally derived from the gastric mucosa. It stimulates growth hormone release, increases appetite and facilitates fat storage, and may interact with glucose metabolism. We studied the ghrelin gene in a group of 70 tall and obese children (mean ag...
Main Authors: | Korbonits, M, Gueorguiev, M, O'Grady, E, Lecoeur, C, Swan, D, Mein, C, Weill, J, Grossman, AB, Froguel, P |
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Format: | Journal article |
Language: | English |
Published: |
2002
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