FRAGMATIC: A randomised phase III clinical trial investigating the effect of fragmin® added to standard therapy in patients with lung cancer

Background: Venous thromboembolism (VTE) occurs when blood clots in the leg, pelvic or other deep vein (deep vein thrombosis) with or without transport of the thrombus into the pulmonary arterial circulation (pulmonary embolus). VTE...

Description complète

Détails bibliographiques
Auteurs principaux:	Griffiths, G, Burns, S, Noble, S, Macbeth, F, Cohen, D, Maughan, T
Format:	Journal article
Langue:	English
Publié:	BioMed Central 2009

Documents similaires

Interim safety data on the FRAGMATIC trial: a randomised phase III clinical trial investigating the effect of FRAGMin (R) added to standard therapy in patients with lung cancer
par: Macbeth, F, et autres
Publié: (2009)

FRAGMATIC: A randomised phase III clinical trial investigating the effect of fragmin® added to standard therapy in patients with lung cancer
par: Macbeth Fergus R, et autres
Publié: (2009-10-01)

Gelsolin-Like Domain 3 Plays Vital Roles in Regulating the Activities of the Lily Villin/Gelsolin/Fragmin Superfamily.
par: Dong Qian, et autres
Publié: (2015-01-01)

Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/− cetuximab in oesophageal cancer
par: Crosby, T, et autres
Publié: (2017)

Standard maintenance therapy versus local consolidative radiation therapy and standard maintenance therapy in 1–5 sites of oligometastatic non-small cell lung cancer: a study protocol of phase III randomised controlled trial
par: Sadhna Kannan, et autres
Publié: (2021-03-01)

Utility of adding oesophageal to endobronchial endosonography when staging lung cancer: a randomised trial
par: Masahide Oki, et autres
Publié: (2024-12-01)

Efficacy of extracranial stereotactic body radiation therapy (SBRT) added to standard treatment in patients with solid tumors (breast, prostate and non-small cell lung cancer) with up to 3 bone-only metastases: study protocol for a randomised phase III trial (STEREO-OS)
par: Sébastien Thureau, et autres
Publié: (2021-02-01)

SCOPE1: a randomised phase II/III multicentre clinical trial of definitive chemoradiation, with or without cetuximab, in carcinoma of the oesophagus
par: Staffurth John N, et autres
Publié: (2011-10-01)

The smoking cessation in pregnancy incentives trial (CPIT): study protocol for a phase III randomised controlled trial
par: Lesley Sinclair, et autres
Publié: (2020-02-01)

Selection criteria for early breast cancer patients in the DBCG proton trial – The randomised phase III trial strategy
par: Line Bjerregaard Stick, et autres
Publié: (2021-03-01)

Reporting of PPI and the MCID in phase III/IV randomised controlled trials—a systematic review
par: Joseph Brennan, et autres
Publié: (2023-05-01)

TROG 18.01 phase III randomised clinical trial of the Novel Integration of New prostate radiation schedules with adJuvant Androgen deprivation: NINJA study protocol
par: Colin I Tang, et autres
Publié: (2019-08-01)

Chemoradiotherapy with or without cetuximab in patients with oesophageal cancer (SCOPE1): a multicentre, phase 2/3 randomised trial.
par: Crosby, T, et autres
Publié: (2013)

A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial
par: Peter Langhorne, et autres
Publié: (2017-09-01)

Open versus laparoscopically-assisted oesophagectomy for cancer: a multicentre randomised controlled phase III trial - the MIRO trial
par: Msika Simon, et autres
Publié: (2011-07-01)

A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: Results of the Panitumumab, Irinotecan and Ciclosporin in COLOrectal cancer therapy trial (PICCOLO)
par: Middleton, G, et autres
Publié: (2013)

A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan and Ciclosporin in COLOrectal cancer therapy trial (PICCOLO).
par: Middleton, G, et autres
Publié: (2013)

A phase III randomised controlled trial of single-dose triple therapy in COPD: the IMPACT protocol
par: Pascoe, S, et autres
Publié: (2016)

Tenecteplase versus alteplase for acute ischaemic stroke: a meta-analysis of phase III randomised trials
par: Yongjun Wang, et autres

Standard or high dose chemoradiotherapy, with or without the protease inhibitor nelfinavir, in patients with locally advanced pancreatic cancer: the phase 1/randomised phase 2 SCALOP-2 trial
par: Mukherjee, S, et autres
Publié: (2024)

Rationale and design of Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events III (TRACE III): a randomised, phase III, open-label, controlled trial
par: Bruce C V Campbell, et autres

Long-term results and recurrence patterns from SCALOP: a phase II randomised trial of gemcitabine- or capecitabine-based chemoradiation for locally advanced pancreatic cancer
par: Hurt, C, et autres
Publié: (2017)

Trends in participant race and sex reporting in lung cancer phase III clinical trials
par: Faaiq N. Aslam, et autres
Publié: (2023-09-01)

Whole-body hypothermia in mild neonatal encephalopathy: protocol for a multicentre phase III randomised controlled trial
par: Garegrat, R, et autres
Publié: (2024)

Effect of early palliative care for patients with glioblastoma (EPCOG): a randomised phase III clinical trial protocol
par: Stephanie Stock, et autres
Publié: (2020-01-01)

Treatment outcomes in patients with seropositive versus seronegative rheumatoid arthritis in Phase III randomised clinical trials of tofacitinib
par: Peter Nash, et autres
Publié: (2019-06-01)

Whole-body hypothermia in mild neonatal encephalopathy: protocol for a multicentre phase III randomised controlled trial
par: Reema Garegrat, et autres
Publié: (2024-07-01)

Fragility index of positive phase II and III randomised clinical trials of treatments for hepatocellular carcinoma (2002–2022)
par: Sabrina Sidali, et autres
Publié: (2023-07-01)

Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial.
par: Mukherjee, S, et autres
Publié: (2013)

Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial
par: Qi Wu, et autres
Publié: (2024-09-01)

CONFIRM: a double-blind, placebo-controlled phase III clinical trial investigating the effect of nivolumab in patients with relapsed mesothelioma: study protocol for a randomised controlled trial
par: Dean A. Fennell, et autres
Publié: (2018-04-01)

Raltitrexed (Tomudex) versus standard leucovorin-modulated bolus 5-fluorouracil: Results from the randomised phase III Pan-European Trial in Adjuvant Colon Cancer 01 (PETACC-1).
par: Popov, I, et autres
Publié: (2008)

Eligibility of patients with advanced non-small cell lung cancer for phase III chemotherapy trials
par: Dadasovich Ryan, et autres
Publié: (2009-04-01)

OP0130 Mepolizumab for the treatment of patients with eosinophilic granulomatosis with polyangiitis: a phase iii randomised, placebo-controlled trial
par: Wechsler, M, et autres
Publié: (2017)

Therapeutic serum level for adalimumab in rheumatoid arthritis: explorative analyses of data from a randomised phase III trial
par: Joseph Sexton, et autres
Publié: (2024-11-01)

AVOID; a phase III, randomised controlled trial using indocyanine green for the prevention of anastomotic leakage in colorectal surgery
par: Hein Putter, et autres
Publié: (2022-04-01)

Heartburn relief with bicarbonate-rich mineral water: results of the randomised, placebo-controlled phase-III trial STOMACH STILL
par: JOACHIM LABENZ, et autres
Publié: (2023-08-01)

Efficacy and safety of iclepertin (BI 425809) in patients with schizophrenia: CONNEX, a Phase III randomised controlled trial programme
par: P. Falkai, et autres
Publié: (2023-03-01)

Cabozantinib Versus Everolimus in Patients with Advanced Renal Cell Carcinoma: Results of a Randomised Phase III Trial (METEOR)
par: Toni Choueiri
Publié: (2015-11-01)

Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - a randomised phase III trial
par: Forder Peta M, et autres
Publié: (2011-04-01)