Two differential binding mechanisms of FG-nucleoporins and nuclear transport receptors

Phenylalanine-glycine-rich nucleoporins (FG-Nups) are intrinsically disordered proteins, constituting the selective barrier of the nuclear pore complex (NPC). Previous studies showed that nuclear transport receptors (NTRs) were found to interact with FG-Nups by forming an "archetypal-fuzzy"...

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Bibliografiska uppgifter
Huvudupphovsmän: Tan, P, Aramburu, I, Mercadante, D, Tyagi, S, Chowdhury, A, Spitz, D, Shammas, S, Gräter, F, Lemke, E
Materialtyp: Journal article
Språk:English
Publicerad: Elsevier 2018