Oxygenation during hypothermic rat liver preservation: an in vitro slice study to demonstrate beneficial or toxic oxygenation effects.

Hypothermic machine perfusion (HMP) of abdominal organs is shown to be superior compared to cold storage. However, the question remains if oxygenation is required during preservation as oxygen is essential for energy resynthesis but also generates toxic reactive oxygen species (ROS). To determine if...

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Détails bibliographiques
Auteurs principaux: 't Hart, N, van der Plaats, A, Faber, A, Leuvenink, H, Olinga, P, Wiersema-Buist, J, Verkerke, G, Rakhorst, G, Ploeg, R
Format: Journal article
Langue:English
Publié: 2005