Robustness assessment using probabilistic scenarios of intensity modulated proton therapy and volumetric arc therapy in non-small-cell lung cancer: an in-silico radiotherapy planning study
Radiotherapy is an essential treatment component for patients with stage III non-small-cell lung cancer. Despite advances, survival remains poor. Proton beam therapy holds the promise of improving cure rates without increasing treatment-related toxicity. However, precision in dose delivery is sensit...
Main Authors: | , , , , |
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Format: | Conference item |
Published: |
Elsevier
2017
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Summary: | Radiotherapy is an essential treatment component for patients with stage III non-small-cell lung cancer. Despite advances, survival remains poor. Proton beam therapy holds the promise of improving cure rates without increasing treatment-related toxicity. However, precision in dose delivery is sensitive to setup uncertainties. The conventional method of adding a margin to account for this problem can be inadequate. We aimed to use the probabilistic scenarios methodology to assess the robustness of intensity modulated proton therapy (IMPT) and volumetric arc therapy (VMAT). |
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