Putative role for interleukin-7 in the maintenance of the recirculating naive CD4+ T-cell pool.

The capacity of the immune system to respond efficiently to new antigens depends upon a continuous source of naive CD4+ T cells. Such cells exit from the thymus and join the recirculated T-cell pool. Factors present at the sites of naive CD4+ T-cell circulation must be responsible for their survival...

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Détails bibliographiques
Auteurs principaux: Webb, L, Foxwell, B, Feldmann, M
Format: Journal article
Langue:English
Publié: 1999