Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure

Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure

Heart failure (HF) is a shared manifestation of several cardiovascular pathologies, including hypertension and myocardial infarction, and a limited repertoire of treatment modalities entails that the associated morbidity and mortality remain high. Impaired nitric oxide (NO)/guanylyl cyclase (GC)/cyc...

Полное описание

Библиографические подробности
Главные авторы:	Baliga, RS, Preedy, MEJ, Dukinfield, MS, Chu, SM, Aubdool, AA, Bubb, KJ, Moyes, AJ, Tones, MA, Hobbs, AJ
Формат:	Journal article
Язык:	English
Опубликовано:	National Academy of Sciences 2018

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