Fetal and neonatal exposure to AZT and low-protein diet affects glucose homeostasis: a model with implications for AIDS prevention.

Fetal and neonatal exposure to AZT and low-protein diet affects glucose homeostasis: a model with implications for AIDS prevention.

Zidovudine (AZT) lowers the perinatal transmission of HIV but can impair mitochondrial function by depleting mitochondrial DNA (mtDNA). AZT therapy and perinatal nutritional deprivation affect the body fat distribution, which influences glucose tolerance. We sought to model intrauterine exposure to...

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Detalhes bibliográficos
Main Authors: Morten, K, Field, P, Ashley, N, Williams, K, Harris, D, Hartley, M, Clark, A, Poulton, J
Formato: Journal article
Idioma:English
Publicado em: 2005

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