Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus.
Novel spatially restricted genetic manipulations can be used to assess contributions made by synaptic plasticity to learning and memory, not just selectively within the hippocampus, but even within specific hippocampal subfields. Here we generated genetically modified mice (NR1(deltaDG) mice) exhibi...
Main Authors: | Niewoehner, B, Single, F, Hvalby, Ø, Jensen, V, Meyer zum Alten Borgloh, S, Seeburg, P, Rawlins, J, Sprengel, R, Bannerman, D |
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Format: | Journal article |
Language: | English |
Published: |
2007
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