A simple bypass assay for DNA polymerases shows that cancer-associated hypermutating variants exhibit differences in vitro

A simple bypass assay for DNA polymerases shows that cancer-associated hypermutating variants exhibit differences in vitro

<p>Errors made by DNA polymerases contribute to both natural variation and, in extreme cases, genome instability and its associated diseases. Recently, the importance of polymerase misincorporation in disease has been highlighted by the identification of cancer-associated polymerase variants w...

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Autors principals:	Crevel, G, Kearsey, S, Cotterill, S
Format:	Journal article
Idioma:	English
Publicat:	Wiley 2023

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