A simple bypass assay for DNA polymerases shows that cancer-associated hypermutating variants exhibit differences in vitro
<p>Errors made by DNA polymerases contribute to both natural variation and, in extreme cases, genome instability and its associated diseases. Recently, the importance of polymerase misincorporation in disease has been highlighted by the identification of cancer-associated polymerase variants w...
Príomhchruthaitheoirí: | Crevel, G, Kearsey, S, Cotterill, S |
---|---|
Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
Wiley
2023
|
Míreanna comhchosúla
Míreanna comhchosúla
-
Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication
de réir: Soriano, I, et al.
Foilsithe / Cruthaithe: (2021) -
Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.
de réir: Ignacio Soriano, et al.
Foilsithe / Cruthaithe: (2021-07-01) -
Enigmatic variations: divergent modes of regulating eukaryotic DNA replication.
de réir: Kearsey, S, et al.
Foilsithe / Cruthaithe: (2003) -
DNAReplication: a database of information and resources for the eukaryotic DNA replication community
de réir: Cotterill, S, et al.
Foilsithe / Cruthaithe: (2009) -
DNAReplication: a database of information and resources for the eukaryotic DNA replication community.
de réir: Cotterill, S, et al.
Foilsithe / Cruthaithe: (2009)