Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4

Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4

The syntheses and preliminary pharmacological characterisation of two novel cyclic phosphinic acid-containing amino acids designed as conformationally restricted analogues of the metabotropic glutamate receptor agonist AP4 (1) are reported.

Xehetasun bibliografikoak
Egile Nagusiak:	Conway, S, Miller, J, Bond, A, Clark, B, Jane, D
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2002

Antzeko izenburuak

Aluminacyclopentanes in the synthesis of 3-substituted phospholanes and α,ω-bisphospholanes
nork: Vladimir A. D’yakonov, et al.
Argitaratua: (2016-03-01)

Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors.
nork: Conway, S, et al.
Argitaratua: (2001)

Metabotropic glutamate receptor agonists for schizophrenia.
nork: Harrison, P
Argitaratua: (2008)

Synthesis of analogues of lycoperdic acid to probe glutamate receptors in the central nervous system
nork: Goundry, W, et al.
Argitaratua: (2003)

Synephrine Analogues as Glucocorticoid Receptor Agonists
nork: Eugenia Oleynik, et al.
Argitaratua: (2023-11-01)

Structural requirements for selective group III metabotropic glutamate receptor antagonists based on the phenylglycine nucleus.
nork: Jane, D, et al.
Argitaratua: (2002)

Novel phenylglycine analogues as potent and selective antagonists of group III mGlu receptors on neonatal rat primary afferent terminals.
nork: Miller, J, et al.
Argitaratua: (2000)

Computational study of synthetic agonist ligands of ionotropic glutamate receptors.
nork: Tino Wolter, et al.
Argitaratua: (2013-01-01)

Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals.
nork: Miller, J, et al.
Argitaratua: (2003)

The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor.
nork: Bryan L Roth, et al.
Argitaratua: (2013-01-01)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors
Argitaratua: (2014-01-01)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors.
nork: Tino Wolter, et al.
Argitaratua: (2014-01-01)

Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor.
nork: Bryan L Roth, et al.
Argitaratua: (2018-01-01)

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity
nork: Stanley, N.J., et al.
Argitaratua: (2010)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
nork: Veerapen, N, et al.
Argitaratua: (2011)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
nork: Veerapen, N, et al.
Argitaratua: (2011)

Synthesis and Biological Evaluation of Novel Biased Mu-Opioid Receptor Agonists
nork: Yanhao Guo, et al.
Argitaratua: (2024-06-01)

Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists
nork: Wenjing Sun, et al.
Argitaratua: (2023-06-01)

Binding site flexibility: Molecular simulation of partial and full agonists within a glutamate receptor
nork: Arinaminpathy, Y, et al.
Argitaratua: (2006)

Binding site flexibility: molecular simulation of partial and full agonists within a glutamate receptor.
nork: Arinaminpathy, Y, et al.
Argitaratua: (2006)

Effects of glutamate receptor agonists on the P13 auditory evoked potential and startle response in the rat
nork: Christen eSimon, et al.
Argitaratua: (2011-01-01)

Direct versatile route to conformationally constrained glutamate analogues
nork: Dyer, J, et al.
Argitaratua: (1998)

Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.
nork: Min-Juan Wang, et al.
Argitaratua: (2013-01-01)

Synthesis and biological evaluation of novel eunicellin analogues
nork: Gilmour, R, et al.
Argitaratua: (2005)

Inositol polyphosphates and analogues: synthesis & chemical biology
nork: Shipton, M
Argitaratua: (2021)

The synthesis and biological evaluation of novel eunicellin analogues
nork: Davidson, J, et al.
Argitaratua: (2004)

Synthesis and Biological Evaluation of New CRH Analogues
nork: Spyridon Papazacharias, et al.
Argitaratua: (2010-01-01)

Synthesis and Biological Evaluation of Aminobisphosphonates—Analogues of Incadronate
nork: Ewa Chmielewska, et al.
Argitaratua: (2019-08-01)

Synthesis and Biological Evaluation of Carbocyclic Analogues of Pachastrissamine
nork: Yongseok Kwon, et al.
Argitaratua: (2015-02-01)

Molecular determinants of agonist selectivity in glutamate-gated chloride channels which likely explain the agonist selectivity of the vertebrate glycine and GABAA-ρ receptors.
nork: Thomas Blarre, et al.
Argitaratua: (2014-01-01)

Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues
nork: Juan Pablo Gonzalez-Gutierrez, et al.
Argitaratua: (2019-07-01)

Defense reaction induced by a metabotropic glutamate receptor agonist microinjected into the dorsal periaqueductal gray of rats
nork: M.L. Molchanov, et al.
Argitaratua: (1999-12-01)

The sigma1 receptor agonist enhances long-term depression caused by activation of metabotropic glutamate receptors in rat hippocampal neurons
nork: Pavel D. Rogozin, et al.
Argitaratua: (2018-12-01)

Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors
nork: Yasushi Matsumuraa, et al.
Argitaratua: (2004-03-01)

Correction: Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABAA-ρ Receptors
Argitaratua: (2014-01-01)

Correction: Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABA-ρ Receptors.
Argitaratua: (2014-01-01)

<it>In vivo </it>antinociception of potent mu opioid agonist tetrapeptide analogues and comparison with a compact opioid agonist - neurokinin 1 receptor antagonist chimera
nork: Guillemyn Karel, et al.
Argitaratua: (2012-01-01)

Synthesis of Polyfluorinated KRN7000 Analogues and Biological Implications
nork: M. Isabel Matheu, et al.
Argitaratua: (2019-08-01)

Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues
nork: Lucie Brulikova, et al.
Argitaratua: (2011-05-01)

Glutamate receptor activation is involved in 5-HT2 agonist-induced Arc gene expression in the rat cortex.
nork: Pei, Q, et al.
Argitaratua: (2004)