Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4

Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4

The syntheses and preliminary pharmacological characterisation of two novel cyclic phosphinic acid-containing amino acids designed as conformationally restricted analogues of the metabotropic glutamate receptor agonist AP4 (1) are reported.

מידע ביבליוגרפי
Main Authors:	Conway, S, Miller, J, Bond, A, Clark, B, Jane, D
פורמט:	Journal article
שפה:	English
יצא לאור:	2002

פריטים דומים

Aluminacyclopentanes in the synthesis of 3-substituted phospholanes and α,ω-bisphospholanes
מאת: Vladimir A. D’yakonov, et al.
יצא לאור: (2016-03-01)

Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors.
מאת: Conway, S, et al.
יצא לאור: (2001)

Metabotropic glutamate receptor agonists for schizophrenia.
מאת: Harrison, P
יצא לאור: (2008)

Synthesis of analogues of lycoperdic acid to probe glutamate receptors in the central nervous system
מאת: Goundry, W, et al.
יצא לאור: (2003)

Synephrine Analogues as Glucocorticoid Receptor Agonists
מאת: Eugenia Oleynik, et al.
יצא לאור: (2023-11-01)

Structural requirements for selective group III metabotropic glutamate receptor antagonists based on the phenylglycine nucleus.
מאת: Jane, D, et al.
יצא לאור: (2002)

Novel phenylglycine analogues as potent and selective antagonists of group III mGlu receptors on neonatal rat primary afferent terminals.
מאת: Miller, J, et al.
יצא לאור: (2000)

Computational study of synthetic agonist ligands of ionotropic glutamate receptors.
מאת: Tino Wolter, et al.
יצא לאור: (2013-01-01)

Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals.
מאת: Miller, J, et al.
יצא לאור: (2003)

The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor.
מאת: Bryan L Roth, et al.
יצא לאור: (2013-01-01)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors
יצא לאור: (2014-01-01)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors.
מאת: Tino Wolter, et al.
יצא לאור: (2014-01-01)

Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor.
מאת: Bryan L Roth, et al.
יצא לאור: (2018-01-01)

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity
מאת: Stanley, N.J., et al.
יצא לאור: (2010)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
מאת: Veerapen, N, et al.
יצא לאור: (2011)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
מאת: Veerapen, N, et al.
יצא לאור: (2011)

Synthesis and Biological Evaluation of Novel Biased Mu-Opioid Receptor Agonists
מאת: Yanhao Guo, et al.
יצא לאור: (2024-06-01)

Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists
מאת: Wenjing Sun, et al.
יצא לאור: (2023-06-01)

Binding site flexibility: Molecular simulation of partial and full agonists within a glutamate receptor
מאת: Arinaminpathy, Y, et al.
יצא לאור: (2006)

Binding site flexibility: molecular simulation of partial and full agonists within a glutamate receptor.
מאת: Arinaminpathy, Y, et al.
יצא לאור: (2006)

Effects of glutamate receptor agonists on the P13 auditory evoked potential and startle response in the rat
מאת: Christen eSimon, et al.
יצא לאור: (2011-01-01)

Direct versatile route to conformationally constrained glutamate analogues
מאת: Dyer, J, et al.
יצא לאור: (1998)

Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.
מאת: Min-Juan Wang, et al.
יצא לאור: (2013-01-01)

Synthesis and biological evaluation of novel eunicellin analogues
מאת: Gilmour, R, et al.
יצא לאור: (2005)

Inositol polyphosphates and analogues: synthesis & chemical biology
מאת: Shipton, M
יצא לאור: (2021)

The synthesis and biological evaluation of novel eunicellin analogues
מאת: Davidson, J, et al.
יצא לאור: (2004)

Synthesis and Biological Evaluation of New CRH Analogues
מאת: Spyridon Papazacharias, et al.
יצא לאור: (2010-01-01)

Synthesis and Biological Evaluation of Aminobisphosphonates—Analogues of Incadronate
מאת: Ewa Chmielewska, et al.
יצא לאור: (2019-08-01)

Synthesis and Biological Evaluation of Carbocyclic Analogues of Pachastrissamine
מאת: Yongseok Kwon, et al.
יצא לאור: (2015-02-01)

Molecular determinants of agonist selectivity in glutamate-gated chloride channels which likely explain the agonist selectivity of the vertebrate glycine and GABAA-ρ receptors.
מאת: Thomas Blarre, et al.
יצא לאור: (2014-01-01)

Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues
מאת: Juan Pablo Gonzalez-Gutierrez, et al.
יצא לאור: (2019-07-01)

Defense reaction induced by a metabotropic glutamate receptor agonist microinjected into the dorsal periaqueductal gray of rats
מאת: M.L. Molchanov, et al.
יצא לאור: (1999-12-01)

The sigma1 receptor agonist enhances long-term depression caused by activation of metabotropic glutamate receptors in rat hippocampal neurons
מאת: Pavel D. Rogozin, et al.
יצא לאור: (2018-12-01)

Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors
מאת: Yasushi Matsumuraa, et al.
יצא לאור: (2004-03-01)

Correction: Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABAA-ρ Receptors
יצא לאור: (2014-01-01)

Correction: Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABA-ρ Receptors.
יצא לאור: (2014-01-01)

<it>In vivo </it>antinociception of potent mu opioid agonist tetrapeptide analogues and comparison with a compact opioid agonist - neurokinin 1 receptor antagonist chimera
מאת: Guillemyn Karel, et al.
יצא לאור: (2012-01-01)

Synthesis of Polyfluorinated KRN7000 Analogues and Biological Implications
מאת: M. Isabel Matheu, et al.
יצא לאור: (2019-08-01)

Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues
מאת: Lucie Brulikova, et al.
יצא לאור: (2011-05-01)

Glutamate receptor activation is involved in 5-HT2 agonist-induced Arc gene expression in the rat cortex.
מאת: Pei, Q, et al.
יצא לאור: (2004)