Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4

Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4

The syntheses and preliminary pharmacological characterisation of two novel cyclic phosphinic acid-containing amino acids designed as conformationally restricted analogues of the metabotropic glutamate receptor agonist AP4 (1) are reported.

書誌詳細
主要な著者:	Conway, S, Miller, J, Bond, A, Clark, B, Jane, D
フォーマット:	Journal article
言語:	English
出版事項:	2002

類似資料

Aluminacyclopentanes in the synthesis of 3-substituted phospholanes and α,ω-bisphospholanes
著者:: Vladimir A. D’yakonov, 等
出版事項: (2016-03-01)

Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors.
著者:: Conway, S, 等
出版事項: (2001)

Metabotropic glutamate receptor agonists for schizophrenia.
著者:: Harrison, P
出版事項: (2008)

Synthesis of analogues of lycoperdic acid to probe glutamate receptors in the central nervous system
著者:: Goundry, W, 等
出版事項: (2003)

Synephrine Analogues as Glucocorticoid Receptor Agonists
著者:: Eugenia Oleynik, 等
出版事項: (2023-11-01)

Structural requirements for selective group III metabotropic glutamate receptor antagonists based on the phenylglycine nucleus.
著者:: Jane, D, 等
出版事項: (2002)

Novel phenylglycine analogues as potent and selective antagonists of group III mGlu receptors on neonatal rat primary afferent terminals.
著者:: Miller, J, 等
出版事項: (2000)

Computational study of synthetic agonist ligands of ionotropic glutamate receptors.
著者:: Tino Wolter, 等
出版事項: (2013-01-01)

Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals.
著者:: Miller, J, 等
出版事項: (2003)

The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor.
著者:: Bryan L Roth, 等
出版事項: (2013-01-01)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors
出版事項: (2014-01-01)

Correction: Computational Study of Synthetic Agonist Ligands of Ionotropic Glutamate Receptors.
著者:: Tino Wolter, 等
出版事項: (2014-01-01)

Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor.
著者:: Bryan L Roth, 等
出版事項: (2018-01-01)

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity
著者:: Stanley, N.J., 等
出版事項: (2010)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
著者:: Veerapen, N, 等
出版事項: (2011)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
著者:: Veerapen, N, 等
出版事項: (2011)

Synthesis and Biological Evaluation of Novel Biased Mu-Opioid Receptor Agonists
著者:: Yanhao Guo, 等
出版事項: (2024-06-01)

Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists
著者:: Wenjing Sun, 等
出版事項: (2023-06-01)

Binding site flexibility: Molecular simulation of partial and full agonists within a glutamate receptor
著者:: Arinaminpathy, Y, 等
出版事項: (2006)

Binding site flexibility: molecular simulation of partial and full agonists within a glutamate receptor.
著者:: Arinaminpathy, Y, 等
出版事項: (2006)

Effects of glutamate receptor agonists on the P13 auditory evoked potential and startle response in the rat
著者:: Christen eSimon, 等
出版事項: (2011-01-01)

Direct versatile route to conformationally constrained glutamate analogues
著者:: Dyer, J, 等
出版事項: (1998)

Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.
著者:: Min-Juan Wang, 等
出版事項: (2013-01-01)

Synthesis and biological evaluation of novel eunicellin analogues
著者:: Gilmour, R, 等
出版事項: (2005)

Inositol polyphosphates and analogues: synthesis & chemical biology
著者:: Shipton, M
出版事項: (2021)

The synthesis and biological evaluation of novel eunicellin analogues
著者:: Davidson, J, 等
出版事項: (2004)

Synthesis and Biological Evaluation of New CRH Analogues
著者:: Spyridon Papazacharias, 等
出版事項: (2010-01-01)

Synthesis and Biological Evaluation of Aminobisphosphonates—Analogues of Incadronate
著者:: Ewa Chmielewska, 等
出版事項: (2019-08-01)

Synthesis and Biological Evaluation of Carbocyclic Analogues of Pachastrissamine
著者:: Yongseok Kwon, 等
出版事項: (2015-02-01)

Molecular determinants of agonist selectivity in glutamate-gated chloride channels which likely explain the agonist selectivity of the vertebrate glycine and GABAA-ρ receptors.
著者:: Thomas Blarre, 等
出版事項: (2014-01-01)

Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues
著者:: Juan Pablo Gonzalez-Gutierrez, 等
出版事項: (2019-07-01)

Defense reaction induced by a metabotropic glutamate receptor agonist microinjected into the dorsal periaqueductal gray of rats
著者:: M.L. Molchanov, 等
出版事項: (1999-12-01)

The sigma1 receptor agonist enhances long-term depression caused by activation of metabotropic glutamate receptors in rat hippocampal neurons
著者:: Pavel D. Rogozin, 等
出版事項: (2018-12-01)

Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors
著者:: Yasushi Matsumuraa, 等
出版事項: (2004-03-01)

Correction: Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABAA-ρ Receptors
出版事項: (2014-01-01)

Correction: Molecular Determinants of Agonist Selectivity in Glutamate-Gated Chloride Channels Which Likely Explain the Agonist Selectivity of the Vertebrate Glycine and GABA-ρ Receptors.
出版事項: (2014-01-01)

<it>In vivo </it>antinociception of potent mu opioid agonist tetrapeptide analogues and comparison with a compact opioid agonist - neurokinin 1 receptor antagonist chimera
著者:: Guillemyn Karel, 等
出版事項: (2012-01-01)

Synthesis of Polyfluorinated KRN7000 Analogues and Biological Implications
著者:: M. Isabel Matheu, 等
出版事項: (2019-08-01)

Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues
著者:: Lucie Brulikova, 等
出版事項: (2011-05-01)

Glutamate receptor activation is involved in 5-HT2 agonist-induced Arc gene expression in the rat cortex.
著者:: Pei, Q, 等
出版事項: (2004)