Mechanistic modelling to determine the limits of clinical and pre-clinical cancer immunotherapies

<p>Immune-mediated clearance of a tumour is predicated on successful activation, migration and engagement of cytotoxic CD8+ T-cells. There are numerous factors that may impede these processes and that vary considerably between patients. In this thesis, I describe the use of mechanistic models...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Brown, L
مؤلفون آخرون: Gaffney, E
التنسيق: أطروحة
اللغة:English
منشور في: 2018
الموضوعات: