Mechanistic modelling to determine the limits of clinical and pre-clinical cancer immunotherapies
<p>Immune-mediated clearance of a tumour is predicated on successful activation, migration and engagement of cytotoxic CD8+ T-cells. There are numerous factors that may impede these processes and that vary considerably between patients. In this thesis, I describe the use of mechanistic models...
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Формат: | Диссертация |
Язык: | English |
Опубликовано: |
2018
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