Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.

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The use of nanoparticles in medicine is ever increasing, and it is important to understand their targeted and non-targeted effects. We have previously shown that nanoparticles can cause DNA damage to cells cultured below a cellular barrier without crossing this barrier. Here, we show that this indir...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Sood, A, Salih, S, Roh, D, Lacharme-Lora, L, Parry, M, Hardiman, B, Keehan, R, Grummer, R, Winterhager, E, Gokhale, P, Andrews, P, Abbott, C, Forbes, K, Westwood, M, Aplin, J, Ingham, E, Papageorgiou, I, Berry, M, Liu, J, Dick, A, Garland, R, Williams, N, Singh, R, Simon, A, Lewis, M
Format: Journal article
Sprache:English
Veröffentlicht: 2011

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