Sampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high-resolution 3D diffusion MRI
<p><strong>Purpose: </strong>To develop a new method for high-fidelity, high-resolution 3D multi-slab diffusion MRI with minimal distortion and boundary slice aliasing.</p> <p><strong>Methods: </strong>Our method modifies 3D multi-slab imag...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Wiley
2023
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| _version_ | 1797112029581934592 |
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| author | Li, Z Miller, KL Andersson, JLR Zhang, J Liu, S Guo, H Wu, W |
| author_facet | Li, Z Miller, KL Andersson, JLR Zhang, J Liu, S Guo, H Wu, W |
| author_sort | Li, Z |
| collection | OXFORD |
| description | <p><strong>Purpose: </strong>To develop a new method for high-fidelity, high-resolution 3D multi-slab diffusion MRI with minimal distortion and boundary slice aliasing.</p>
<p><strong>Methods: </strong>Our method modifies 3D multi-slab imaging to integrate blip-reversed acquisitions for distortion correction and oversampling in the slice direction (k<sub>z</sub>) for reducing boundary slice aliasing. Our aim is to achieve robust acceleration to keep the scan time the same as conventional 3D multi-slab acquisitions, in which data are acquired with a single direction of blip traversal and without k<sub>z</sub>-oversampling. We employ a two-stage reconstruction. In the first stage, the blip-up/down images are respectively reconstructed and analyzed to produce a field map for each diffusion direction. In the second stage, the blip-reversed data and the field map are incorporated into a joint reconstruction to produce images that are corrected for distortion and boundary slice aliasing.</p>
<p><strong>Results: </strong>We conducted experiments at 7T in six healthy subjects. Stage 1 reconstruction produces images from highly under-sampled data (<em>R</em> = 7.2) with sufficient quality to provide accurate field map estimation. Stage 2 joint reconstruction substantially reduces distortion artifacts with comparable quality to fully-sampled blip-reversed results (2.4× scan time). Whole-brain in-vivo results acquired at 1.22 mm and 1.05 mm isotropic resolutions demonstrate improved anatomical fidelity compared to conventional 3D multi-slab imaging. Data demonstrate good reliability and reproducibility of the proposed method over multiple subjects.</p>
<p><strong>Conclusion: </strong>The proposed acquisition and reconstruction framework provide major reductions in distortion and boundary slice aliasing for 3D multi-slab diffusion MRI without increasing the scan time, which can potentially produce high-quality, high-resolution diffusion MRI.</p> |
| first_indexed | 2024-03-07T08:18:36Z |
| format | Journal article |
| id | oxford-uuid:5a6ef0b8-f478-4140-b602-d057b5b10067 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T08:18:36Z |
| publishDate | 2023 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:5a6ef0b8-f478-4140-b602-d057b5b100672024-01-19T10:50:16ZSampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high-resolution 3D diffusion MRIJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5a6ef0b8-f478-4140-b602-d057b5b10067EnglishSymplectic ElementsWiley2023Li, ZMiller, KLAndersson, JLRZhang, JLiu, SGuo, HWu, W<p><strong>Purpose: </strong>To develop a new method for high-fidelity, high-resolution 3D multi-slab diffusion MRI with minimal distortion and boundary slice aliasing.</p> <p><strong>Methods: </strong>Our method modifies 3D multi-slab imaging to integrate blip-reversed acquisitions for distortion correction and oversampling in the slice direction (k<sub>z</sub>) for reducing boundary slice aliasing. Our aim is to achieve robust acceleration to keep the scan time the same as conventional 3D multi-slab acquisitions, in which data are acquired with a single direction of blip traversal and without k<sub>z</sub>-oversampling. We employ a two-stage reconstruction. In the first stage, the blip-up/down images are respectively reconstructed and analyzed to produce a field map for each diffusion direction. In the second stage, the blip-reversed data and the field map are incorporated into a joint reconstruction to produce images that are corrected for distortion and boundary slice aliasing.</p> <p><strong>Results: </strong>We conducted experiments at 7T in six healthy subjects. Stage 1 reconstruction produces images from highly under-sampled data (<em>R</em> = 7.2) with sufficient quality to provide accurate field map estimation. Stage 2 joint reconstruction substantially reduces distortion artifacts with comparable quality to fully-sampled blip-reversed results (2.4× scan time). Whole-brain in-vivo results acquired at 1.22 mm and 1.05 mm isotropic resolutions demonstrate improved anatomical fidelity compared to conventional 3D multi-slab imaging. Data demonstrate good reliability and reproducibility of the proposed method over multiple subjects.</p> <p><strong>Conclusion: </strong>The proposed acquisition and reconstruction framework provide major reductions in distortion and boundary slice aliasing for 3D multi-slab diffusion MRI without increasing the scan time, which can potentially produce high-quality, high-resolution diffusion MRI.</p> |
| spellingShingle | Li, Z Miller, KL Andersson, JLR Zhang, J Liu, S Guo, H Wu, W Sampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high-resolution 3D diffusion MRI |
| title | Sampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high-resolution 3D diffusion MRI |
| title_full | Sampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high-resolution 3D diffusion MRI |
| title_fullStr | Sampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high-resolution 3D diffusion MRI |
| title_full_unstemmed | Sampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high-resolution 3D diffusion MRI |
| title_short | Sampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high-resolution 3D diffusion MRI |
| title_sort | sampling strategies and integrated reconstruction for reducing distortion and boundary slice aliasing in high resolution 3d diffusion mri |
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