Controlled glycosylation of therapeutic antibodies in plants.

Controlled glycosylation of therapeutic antibodies in plants.

Recombinant therapeutic monoclonal antibodies (mAb) can be expressed, assembled, and glycosylated in plants. Transgenic plants, producing anti-rabies mAb and anti-colorectal cancer mAb, were obtained from Agrobacterium-mediated transformation. The heavy chain (HC) of anti-rabies mAb was fused to the...

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Autors principals:	Tekoah, Y, Ko, K, Koprowski, H, Harvey, D, Wormald, M, Dwek, R, Rudd, P
Format:	Journal article
Idioma:	English
Publicat:	2004

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