Controlled glycosylation of therapeutic antibodies in plants.

Controlled glycosylation of therapeutic antibodies in plants.

Recombinant therapeutic monoclonal antibodies (mAb) can be expressed, assembled, and glycosylated in plants. Transgenic plants, producing anti-rabies mAb and anti-colorectal cancer mAb, were obtained from Agrobacterium-mediated transformation. The heavy chain (HC) of anti-rabies mAb was fused to the...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Tekoah, Y, Ko, K, Koprowski, H, Harvey, D, Wormald, M, Dwek, R, Rudd, P
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2004

समान संसाधन

Glycosylation and prion protein.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (2002)

Exploring functions for glycosylation in host defence using novel oligosaccharide sequencing technology
द्वारा: Rudd, P, और अन्य
प्रकाशित: (2000)

Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis.
द्वारा: Saldova, R, और अन्य
प्रकाशित: (2008)

O-linked glycosylation in focus
द्वारा: Van den Steen, P, और अन्य
प्रकाशित: (2000)

The impact of glycosylation on the biological function and structure of human immunoglobulins.
द्वारा: Arnold, J, और अन्य
प्रकाशित: (2007)

Matrix remodelling enzymes, the protease cascade and glycosylation.
द्वारा: Van den Steen, P, और अन्य
प्रकाशित: (2001)

Roles for glycosylation in the anti-inflammatory molecule CD59.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (1997)

The glycosylation of the complement regulatory protein, human erythrocyte CD59.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (1998)

The glycosylation of the complement regulatory protein, human erythrocyte CD59.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (1997)

Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin.
द्वारा: Arnold, J, और अन्य
प्रकाशित: (2005)

Glycosylation influences the lectin activities of the mannose receptor
द्वारा: Yunpeng, Y, और अन्य
प्रकाशित: (2005)

The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin.
द्वारा: Arnold, J, और अन्य
प्रकाशित: (2004)

Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (2000)

Glycosylation influences the lectin activities of the macrophage mannose receptor.
द्वारा: Su, Y, और अन्य
प्रकाशित: (2005)

Direct deprotected glycosyl-asparagine ligation.
द्वारा: Doores, K, और अन्य
प्रकाशित: (2006)

Intracellular reprogramming of expression, glycosylation, and function of a plant-derived antiviral therapeutic monoclonal antibody.
द्वारा: Jeong-Hwan Lee, और अन्य
प्रकाशित: (2013-01-01)

Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.
द्वारा: Jacquemin, M, और अन्य
प्रकाशित: (2006)

Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs
द्वारा: Zhang, P, और अन्य
प्रकाशित: (2016)

Structural aspects of glycomes with a focus on N-glycosylation and glycoprotein folding.
द्वारा: Petrescu, A, और अन्य
प्रकाशित: (2006)

Differential glycosylation of gelatinase B from neutrophils and breast cancer cells.
द्वारा: Fry, SA, और अन्य
प्रकाशित: (2005)

Targeting glycosylation as a therapeutic approach.
द्वारा: Dwek, R, और अन्य
प्रकाशित: (2002)

Emerging principles for the therapeutic exploitation of glycosylation.
द्वारा: Dalziel, M, और अन्य
प्रकाशित: (2014)

Optimal synthetic glycosylation of a therapeutic antibody
द्वारा: Parsons, T, और अन्य
प्रकाशित: (2016)

Remnant epitopes, autoimmunity and glycosylation.
द्वारा: Opdenakker, G, और अन्य
प्रकाशित: (2006)

Glycosylation: disease targets and therapy.
द्वारा: Zitzmann, N, और अन्य
प्रकाशित: (2005)

Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding.
द्वारा: Petrescu, A, और अन्य
प्रकाशित: (2004)

Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
द्वारा: Butters, T, और अन्य
प्रकाशित: (2000)

Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy
द्वारा: Yusuke Mimura, और अन्य
प्रकाशित: (2017-06-01)

Sugar-mediated ligand-receptor interactions in the immune system.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (2004)

Glycosylation influences the ligand binding activities of mannose receptor.
द्वारा: Su, Y, और अन्य
प्रकाशित: (2005)

"Internal residue loss": rearrangements occurring during the fragmentation of carbohydrates derivatized at the reducing terminus.
द्वारा: Harvey, D, और अन्य
प्रकाशित: (2002)

Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway.
द्वारा: Crispin, M, और अन्य
प्रकाशित: (2006)

Mutations at critical N-glycosylation sites reduce tyrosinase activity by altering folding and quality control.
द्वारा: Branza-Nichita, N, और अन्य
प्रकाशित: (2000)

Glycosylation markers for cancer diagnosing and monitoring
द्वारा: Dwek, R, और अन्य
प्रकाशित: (2006)

Roles of quaternary architectures in immunoglobulin glycosylation and antibody-based therapeutics
द्वारा: Le, N
प्रकाशित: (2018)

The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors.
द्वारा: Van den Steen, P, और अन्य
प्रकाशित: (2006)

Antibody Glycosylation and Inflammation
द्वारा: Robert M. Anthony, और अन्य
प्रकाशित: (2013-06-01)

Prion glycoprotein: structure, dynamics, and roles for the sugars.
द्वारा: Rudd, P, और अन्य
प्रकाशित: (2001)

N-Glycosylation of Recombinant Therapeutic Glycoproteins in Plant Systems
द्वारा: Marijana Krsnik-Rasol, और अन्य
प्रकाशित: (2007-01-01)

Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides.
द्वारा: Tsiftsoglou, SA, और अन्य
प्रकाशित: (2006)