Controlled glycosylation of therapeutic antibodies in plants.

Recombinant therapeutic monoclonal antibodies (mAb) can be expressed, assembled, and glycosylated in plants. Transgenic plants, producing anti-rabies mAb and anti-colorectal cancer mAb, were obtained from Agrobacterium-mediated transformation. The heavy chain (HC) of anti-rabies mAb was fused to the...

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Những tác giả chính: Tekoah, Y, Ko, K, Koprowski, H, Harvey, D, Wormald, M, Dwek, R, Rudd, P
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2004