The pathogenesis of multiple sclerosis: is it really a primary inflammatory process?

The pathogenesis of multiple sclerosis (MS) remains unknown. Although inflammation, demyelination and axonal injury are all involved, the primary pathogenic process is not clear. In this paper we challenge the hypothesis that MS is a primary inflammatory condition, and suggest that axonal damage may...

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Bibliographic Details
Main Authors: Maggs, F, Palace, J
Format: Journal article
Language:English
Published: 2004
Description
Summary:The pathogenesis of multiple sclerosis (MS) remains unknown. Although inflammation, demyelination and axonal injury are all involved, the primary pathogenic process is not clear. In this paper we challenge the hypothesis that MS is a primary inflammatory condition, and suggest that axonal damage may occur independently.