Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.

Chloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirme...

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Main Authors: Rijken, M, Boel, M, Russell, B, Imwong, M, Leimanis, M, Phyo, A, Muehlenbachs, A, Lindegardh, N, Mcgready, R, Rénia, L, Snounou, G, Singhasivanon, P, Nosten, F
Format: Journal article
Jezik:English
Izdano: BioMed Central 2011
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author Rijken, M
Boel, M
Russell, B
Imwong, M
Leimanis, M
Phyo, A
Muehlenbachs, A
Lindegardh, N
Mcgready, R
Rénia, L
Snounou, G
Singhasivanon, P
Nosten, F
author_facet Rijken, M
Boel, M
Russell, B
Imwong, M
Leimanis, M
Phyo, A
Muehlenbachs, A
Lindegardh, N
Mcgready, R
Rénia, L
Snounou, G
Singhasivanon, P
Nosten, F
author_sort Rijken, M
collection OXFORD
description Chloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirmed in-vitro and molecular genotyping was strongly suggestive of true recrudescence of P. vivax. This is the first clinically and laboratory confirmed case of two high-grade CQ resistant vivax parasite strains from Thailand.
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spelling oxford-uuid:5acec569-79b5-43bd-a57d-edb8007966fb2022-03-26T17:18:09ZChloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5acec569-79b5-43bd-a57d-edb8007966fbEnglishSymplectic Elements at OxfordBioMed Central2011Rijken, MBoel, MRussell, BImwong, MLeimanis, MPhyo, AMuehlenbachs, ALindegardh, NMcgready, RRénia, LSnounou, GSinghasivanon, PNosten, FChloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirmed in-vitro and molecular genotyping was strongly suggestive of true recrudescence of P. vivax. This is the first clinically and laboratory confirmed case of two high-grade CQ resistant vivax parasite strains from Thailand.
spellingShingle Rijken, M
Boel, M
Russell, B
Imwong, M
Leimanis, M
Phyo, A
Muehlenbachs, A
Lindegardh, N
Mcgready, R
Rénia, L
Snounou, G
Singhasivanon, P
Nosten, F
Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.
title Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.
title_full Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.
title_fullStr Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.
title_full_unstemmed Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.
title_short Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.
title_sort chloroquine resistant vivax malaria in a pregnant woman on the western border of thailand
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